Deans' stroke musings: Bladder Cancer Treatment May Lower Risk for Alzheimer and Related Dementias

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, June 23, 2023

Bladder Cancer Treatment May Lower Risk for Alzheimer and Related Dementias

FYI, for your doctor to consider because of your higher risk of dementia due to your stroke.

Your risk of dementia, has your doctor told you of this? Your doctor is responsible for preventing this!

1. A documented 33% dementia chance post-stroke from an Australian study? May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`

3. A 20% chance in this research. July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018

The latest here:

Bladder Cancer Treatment May Lower Risk for Alzheimer and Related Dementias

HealthDay News — The bacillus Calmette-Guerin (BCG) vaccine is associated with a significantly lower rate and risk for Alzheimer disease and related dementias (ADRD) among patients with bladder cancer, according to a study published online May 19 in JAMA Network Open.

Marc S. Weinberg, M.D., Ph.D., from Massachusetts General Hospital in Boston, and colleagues evaluated whether the BCG vaccine (3,388 patients) has a protective association with the risk for ADRD. The analysis included 6,467 patients (aged 50 years and older) initially diagnosed with nonmuscle-invasive bladder cancer between May 28, 1987, and May 6, 2021.

Researchers found that treatment with the BCG vaccine was associated with a lower rate of ADRD (hazard ratio [HR], 0.80), with an even lower rate of ADRD in patients aged 70 years or older at the time of BCG vaccine treatment (HR, 0.74). The BCG vaccine was associated with a lower risk for ADRD (5-year risk difference, −0.011) and a decreased risk for death in patients without an earlier diagnosis of ADRD (5-year risk difference, −0.056) in a competing risks analysis.

“In this study, BCG vaccine was associated with a significantly lower rate and risk of ADRD in a cohort of patients with bladder cancer when accounting for death as a competing event. However, the risk differences varied with time,” the authors write. “Clinical trials are required to study its efficacy beyond treatment in patients with bladder cancer.”

Several authors disclosed ties to the biotechnology and pharmaceutical industries.