Deans' stroke musings: Brain Junctions Unlocked

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, January 14, 2024

Brain Junctions Unlocked

Ask your doctors EXACTLY how using this information will get you recovered! If your doctor has no idea, you don't have a functioning stroke doctor!

RUN AWAY!

Ask your doctor point blank. 'Does stroke cause demylination?' If it does then what is your doctor doing to get research going on this?

Brain Junctions Unlocked

Summary: New research unveils the function of a previously little-understood brain junction involving oligodendrocyte precursor cells (OPCs). These cells, integral in forming the protective myelin sheath around nerve cells, have been found to form unique synapses with neurons, influencing myelin production.

This discovery, made possible by advanced imaging techniques in zebrafish, could have significant implications for treating a range of conditions from multiple sclerosis to Alzheimer’s disease and even glioma. The study suggests that manipulating these neuron-OPC synapses could offer new methods for disease intervention, particularly in demyelinating disorders.

Key Facts:

The neuron-OPC synapse plays a crucial role in the formation of the myelin sheath, a protective layer around nerve cells.
This discovery could impact the treatment of neurological conditions like multiple sclerosis, Alzheimer’s, and glioma by targeting these synapses for therapeutic intervention.
OPCs, making up about 5% of brain cells, have functions beyond forming oligodendrocytes, possibly playing a broader role in brain health and disease.

Source: Oregon Health and Science University

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer’s disease, to a type of brain cancer known as glioma.

The study published today in the journal Nature Neuroscience.

Neuroscientists focused on the junction, or synapse, connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells, or OPCs. OPCs can differentiate into oligodendrocytes, which produce a sheath around nerves known as myelin. Myelin is the protective sheath covering each nerve cell’s axon — the threadlike portion of a cell that transmits electrical signals between cells.