Deans' stroke musings: TyG index signals higher risk after EVT in large-core ischemic stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, February 16, 2026

TyG index signals higher risk after EVT in large-core ischemic stroke

What will it take to change the status quo and reduce the risk to nothing?

Do you prefer your doctor, hospital and board of director's incompetence NOT KNOWING? OR NOT DOING? Your choice; let them be incompetent or demand action!

TyG index signals higher risk after EVT in large-core ischemic stroke

This study aims to evaluate the association between the triglyceride-glucose (TyG) index and the prognosis of patients with large ischemic core stroke received or did not receive endovascular treatment (EVT). This subanalysis from a multicenter, prospective registry study focused on patients with large ischemic core stroke. TyG, calculated by ln(triglycerides [mg/dL] × glucose [mg/dL]/2), was evaluated as both a four quartiles variable (⩽8.36 vs 8.36-8.85 vs 8.85-9.40 vs ⩾9.40) and a continuous variable. The primary outcome was the mRS score at 90 days, and the safety outcome was the 90-day mortality. Study registered at Chictr.org.cn (ChiCTR2100051664). Among 588 patients (54.4% men, median age 70 years), a higher continuous TyG index was associated with worse 3-month functional outcomes and increased mortality (adjusted odds ratio, 0.63; 95% confidence interval 0.50-0.78, p < 0.001; adjusted odds ratio, 1.6; 95% confidence interval, 1.31-2.18, p < 0.001). This association remained significant when TyG was treated categorically. A significant interaction between TyG index and treatment modalities was observed (p = 0.02). When the TyG index exceeded 9.18, the risk of death significantly increased in the EVT group. The TyG index more strongly associated with prognosis in EVT patients. Benefit of EVT became nonsignificant when TyG index exceeded 9.18.