Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, January 5, 2026

Sleep for Stroke Management and Recovery Trial

 

 I have a mild case of sleep apnea (6.5 times an hour), use of a CPAP makes it impossible for me to sleep. My doctor never considered my exhaustion could be sleep apnea rather than the stroke, but then he never knew anything about stroke either. I quit using it so I could actually sleep, no clue if it still exists, no partner to tell me otherwise.

The latest here:

Sleep for Stroke Management and Recovery Trial

ClinicalTrials.gov IDNCT03812653
SponsorUniversity of Michigan
Information Provided byDevin Brown, MD, MS
Study Start (Actual)2019-05-09
Primary Completion (Estimated) 2026-11
Study Completion (Estimated)2026-11
Enrollment (Estimated)3062
Study TypeInterventional
Last Update Posted2025-12-19

Brief Summary

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

Contact Information

Study Contact

NameKayla Novitski, MPH, CCRP

PhoneNot available

Study Contact Backup

NameJoelle Sickler, MSN, CCRC, CCRA

PhoneNot available


United States Locations

 

Alabama

Birmingham, Alabama, United States 35294 University of Alabama Hospital 

Arizona

Chandler, Arizona, United States 85224 Chandler Regional Medical Center

Phoenix, Arizona, United States 85006

Banner University Medical Center Phoenix

Phoenix, Arizona, United States 85013

Dignity Health - St. Joseph's Hospital and Medical Center

Tucson, Arizona, United States 85712

TMC Healthcare

Tucson, Arizona, United States 85719

Banner- University Medical Center Tucson

California

Carmichael, California, United States 95608

Mercy San Juan Medical Center

Downey, California, United States 90242

Rancho Los Amigos National Rehabilitation Center

La Jolla, California, United States 92037

Scripps Memorial

La Jolla, California, United States 92103

UCSD Health La Jolla

Los Angeles, California, United States 90048

Cedars-Sinai Medical Center

Los Angeles, California, United States 90095

Ronald Reagan UCLA Medical Center

Los Angeles, California, United States 94612

Kaiser Permanente Los Angeles

Modesto, California, United States 95355

Doctors Medical Center of Modesto

Ontario, California, United States 91761

UCLA Kaiser Fontana

Orange, California, United States 92868

UC Irvine

Pomona, California, United States 91767

Casa Colina

Redwood City, California, United States 94063

Kaiser Redwood

Sacramento, California, United States 95817

UC Davis Medical Center

San Diego, California, United States 92103

UCSD Medical Center - Hillcrest Hospital

San Francisco, California, United States 94143

UCSF Helen Diller Medical Center at Parnassus Heights

Santa Ana, California, United States 92705

Orange County Global Medical Center

Sylmar, California, United States 91342

Olive View- UCLA Medical Center

Walnut Creek, California, United States 94598

John Muir Medical Center- Walnut Creek Campus

Colorado

Grand Junction, Colorado, United States 81501

St. Mary's Hospital and Medical Center

Connecticut

Hartford, Connecticut, United States 06102

Hartford Hospital

New Haven, Connecticut, United States 06510

Yale-New Haven Hospital

District of Columbia

Washington D.C., District of Columbia, United States 20037

George Washington University Hospital

Florida

Clearwater, Florida, United States 33756

Morton Plant Hospital

Fort Lauderdale, Florida, United States 33305

Broward Health

Gainesville, Florida, United States 32611

UF Health Shands Hospital

Jacksonville, Florida, United States 32209

UF Jacksonville

Jacksonville, Florida, United States 32216

Brooks Rehabilitation Hospital

Miami, Florida, United States 33136

Jackson Memorial Hospital

Miami, Florida, United States 33176

Baptist Hospital of Miami

Sarasota, Florida, United States 34239

Sarasota Memorial Hospital

Tampa, Florida, United States 33606

Tampa General Hospital

Tampa, Florida, United States 33607

St. Joseph's Hospital

Georgia

Atlanta, Georgia, United States 30303

Grady Memorial Hospital

Illinois

Chicago, Illinois, United States 60612

Rush University Medical Center

Chicago, Illinois, United States 60612

University of Illinois Hospital and Health Sciences System

Chicago, Illinois, United States 60637

University of Chicago

Peoria, Illinois, United States 61603

OSF Saint Francis Medical Center

Springfield, Illinois, United States 62702

Memorial Medical Center

Iowa

Des Moines, Iowa, United States 50309

Iowa Methodist

Iowa City, Iowa, United States 52242

University of Iowa Hospitals and Clinics

Kentucky

Louisville, Kentucky, United States 40218

Norton HealthCare

Louisiana

New Orleans, Louisiana, United States 70121

Ochsner Medical Center - Main Campus

Shreveport, Louisiana, United States 71103

University Health Shreveport

Maryland

Baltimore, Maryland, United States 21201

University of Maryland

Massachusetts

Boston, Massachusetts, United States 02111

Tufts Medical Center

Boston, Massachusetts, United States 02114

Massachusetts General Hospital

Boston, Massachusetts, United States 02215

Beth Israel Deaconess Medical Center

Worcester, Massachusetts, United States 01655

UMass Memorial Medical Center,

Michigan

Detroit, Michigan, United States 48202

Henry Ford Hospital

Flint, Michigan, United States 48532

McLaren Flint

Grand Rapids, Michigan, United States 49503

Trinity Health Saint Mary's

Kalamazoo, Michigan, United States 49008

Bronson Methodist Hospital

Minnesota

Rochester, Minnesota, United States 55905

Mayo Clinic Saint Marys Campus

Saint Cloud, Minnesota, United States 56303

Saint Cloud/Centracare Health

Mississippi

Jackson, Mississippi, United States 39216

University of Mississippi Medical Center

Missouri

Kansas City, Missouri, United States 64111

Saint Luke's Hospital of Kansas City

Springfield, Missouri, United States 65807

Cox Medical Center

St Louis, Missouri, United States 63110

Barnes-Jewish Hospital

Nebraska

Omaha, Nebraska, United States 68198

University of Nebraska Medical Center

New Jersey

Edison, New Jersey, United States 08820

JFK Neuroscience Institute

Livingston, New Jersey, United States 07039

Cooperman Barnabas Medical Center

Neptune City, New Jersey, United States 07753

Hackensack Meridian Jersey Shore University Medical Center

New Mexico

Albuquerque, New Mexico, United States 87106

University of New Mexico Hospital

New York

Brooklyn, New York, United States 11219

Maimonides Medical Center

Brooklyn, New York, United States 11220

NYU Langone Brooklyn

Buffalo, New York, United States 14203

Buffalo General Medical Center

Manhasset, New York, United States 11030

North Shore University Hospital

New York, New York, United States 10016

Bellevue Hospital

New York, New York, United States 10016

NYU Langone -Tish Hospital Medical Center

New York, New York, United States 10032

NYP Columbia University Medical Center

Rochester, New York, United States 14642

Strong Memorial Hospital

Staten Island, New York, United States 10305

Staten Island University Hospital

Syracuse, New York, United States 13210

Suny Upstate Medical University

The Bronx, New York, United States 10467

Montefiore Medical Center

North Carolina

Charlotte, North Carolina, United States 28203

Carolinas Medical Center Atrium Health

Concord, North Carolina, United States 28025

Carolinas Rehab Northeast

Greensboro, North Carolina, United States 27401

Guilford Neurologic Associates, Inc

Winston-Salem, North Carolina, United States 27157

Wake Forest University Baptist Medical Center

Ohio

Cincinnati, Ohio, United States 45219

Christ Hospital

Cincinnati, Ohio, United States 45219

University of Cincinnati Medical Center

Cleveland, Ohio, United States 11100

UH Cleveland Medical Center

Cleveland, Ohio, United States 44195

Cleveland Clinic

Columbus, Ohio, United States 43210

OSU Wexner Medical Center

West Chester, Ohio, United States 45069

West Chester Hospital

Oklahoma

Tulsa, Oklahoma, United States 74104

St. John Health System

Oregon

Portland, Oregon, United States 97225

Providence St. Vincent Medical Center

Pennsylvania

Bethlehem, Pennsylvania, United States 18015

St. Luke's University Hospital Bethlehem Campus

Danville, Pennsylvania, United States 17822

Geisinger Clinic

Hershey, Pennsylvania, United States 17033

Penn State Milton S. Hershey Center

Philadelphia, Pennsylvania, United States 19104

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States 19122

Temple University Hospital

Pittsburgh, Pennsylvania, United States 15213

UPMC Presbyterian Hospital

South Carolina

Columbia, South Carolina, United States 29203

Palmetto Health Richland

Greenville, South Carolina, United States 29605

Greenville Memorial Hospital

South Dakota

Sioux Falls, South Dakota, United States 57108

Avera Research Institute

Tennessee

Knoxville, Tennessee, United States 37916

Fort Sanders Regional Medical Center

Memphis, Tennessee, United States 38105

Methodist University

Texas

Dallas, Texas, United States 75246

Baylor Scott & White Institute of Rehabilitation

Houston, Texas, United States 77030

Memorial Hermann Texas Medical Center

Utah

Murray, Utah, United States 84107

Intermountain Medical Center

Salt Lake City, Utah, United States 84132

University of Utah Healthcare

Vermont

Burlington, Vermont, United States 05401

The University of Vermont Medical Center Main Campus

Virginia

Charlottesville, Virginia, United States 22908

UVA Medical Center

Falls Church, Virginia, United States 22042

Inova Fairfax

Richmond, Virginia, United States 23219

Virginia Commonwealth University

Washington

Seattle, Washington, United States 98101

Virginia Mason Medical Center

Seattle, Washington, United States 98195

Harborview Medical Center

West Virginia

Morgantown, West Virginia, United States 26506

Ruby Memorial Hospital

Wisconsin

La Crosse, Wisconsin, United States 54601

Gundersen Lutheran Medical Foundation

Madison, Wisconsin, United States 53715

University of Wisconsin University Hospital

Participation CriteriaEligibility CriteriaCurrent Inclusion Criteria, as of 6/28/2024:
    Ischemic stroke within the prior 7 days.
  • NIH Stroke Scale Score ≥1 at the time of enrollment
  • Previous Inclusion Criteria, prior to 6/28/2024:

     

    1. Ischemic stroke or TIA with ABCD ≥4, within prior 14 days.

     

    Exclusion Criteria (for entire time period):

    1. pre-event inability to perform all of own basic ADLs
    2. unable to obtain informed consent from subject or legally authorized representative
    3. incarcerated
    4. known pregnancy
    5. current mechanical ventilation (can enroll later if this resolves) or tracheostomy
    6. current use of positive airway pressure, or use within one month prior to stroke
    7. anatomical or dermatologic anomaly that makes use of CPAP interface unfeasible
    8. severe bullous lung disease
    9. history of prior spontaneous pneumothorax or current pneumothorax
    10. hypotension requiring current treatment with pressors (can enroll later if this resolves)
    11. other specific medical circumstances that conceivably, in the opinion of the site PI, could render the patient at risk of harm from use of CPAP
    12. massive epistaxis or previous history of massive epistaxis
    13. cranial surgery or head trauma within the past 6 months, with known or possible CSF leak or pneumocephalus
    14. recent hemicraniectomy or suboccipital craniectomy (i.e. those whose bone has not yet been replaced), or any other recent bone removal procedure for relief of intracranial pressure
    15. current receipt of oxygen supplementation >4 liters per minute
    16. current contact, droplet, respiratory/airborne precautions

    Ages Eligible for Study

    Minimum Eligible Age Not available

    Maximum Eligible Age Elderly

    Age Groups adult, older_adult

    Eligible Sexes all

    Accepts Healthy VolunteersNo

    Sampling Method Non-Probability Sample

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